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Know what is mole, simple definition of mole in chemistry, how to calculate number of moles, mass from moles, moles from volume, molar mass A mole is a unit of quantity that describes the number of particles in a system. Learn how to use the mole to calculate mass, number of molecules, and molar mass with examples and references. Mole can be defined as the amount of substance that contains the same number of entities (atoms, molecules, ions etc) as the number of atoms present in 12g of the carbon −12 isotope. Learn what a mole is and how to calculate the number of moles, molar mass, and related quantities of a substance. A mole is the amount of a substance that contains exactly 6.02214076 " 1023 elementary entities.