What is Considered a Dangerous Level of Bilirubin in Adults? A bilirubin level of above 2.5 mg/dL is generally considered elevated and may start showing visible symptoms like jaundice (yellowing of skin and eyes). Bilirubin is an orange-yellow bile pigment formed during the normal breakdown of the red blood cells. Learn about the elevated bilirubin level and its problems. Above 15 or 20 mg/dL are typically considered to be Dangerous bilirubin levels in adults. Know what bilirubin levels signal health issues like jaundice. Find out a range chart, symptoms, and testing insights. This article defines bilirubin and examines the causes of elevated bilirubin levels in adults and newborns. It also looks at the symptoms and treatment options for high bilirubin levels.