Vitamin K (VK) deficiency (VKD) commonly causes coagulopathy across the age spectrum. The reduced form of VK is an essential cofactor for the post-translational γ-carboxylation of coagulation factors (Fs) II, VII, IX, and X; proteins C and S; and ... Vitamin K comprises a group of fat-soluble compounds. Several vitamin K -dependent proteins are involved in essential processes such as blood clotting, bone metabolism, and cardiovascular health. Vitamin K deficiency can contribute to significant bleeding, poor bone development, osteoporosis, and increased cardiovascular disease. According to the National Academy of Science Food and Nutrition Board, the recommended dietary intake for healthy adults is 120 μg/d for men and 90 μg/d for women. Vitamin K is an essential fat-soluble vitamin which is important to bone and heart health, as well as blood clotting and brain function. A deficiency of vitamin K is rare in healthy adults due to its presence in a variety of common dietary sources, including green leafy vegetables, oils and grains. While newborn babies are particularly at risk, people of any age can develop a vitamin K deficiency , which may be triggered by a number of factors, including liver disease, malnutrition and as a ... Being vitamin K deficient affects the circulatory system, immune system, brain, and more. Learn how symptoms of vitamin K deficiency present.
