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Platelets are small blood cells with several physiological purposes; the best studied is thrombosis activation. Through their clotting activity and activation of the coagulation cascade, they are crucial to maintaining adequate blood volume in those with vascular injury. The initiation of this activity begins with tissue injury and results in the release and binding of several glycoproteins, growth factors, and clotting factors. The complexity of these processes allows for many pharmacologic ... Platelets are the cells that circulate within our blood and bind together when they recognize damaged blood vessels. A platelet count measures the average platelet level in a person’s blood. Platelets are crucial to wound healing and clotting, and abnormal levels can indicate various health conditions. Platelets are blood cells that form clots to stop bleeding. Learn about their origin, shape, granules, receptors, and role in hemostasis and immunity.