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What does the word "nuance" mean and how do you use it in a sentence? Learn the meaning and definition of “nuance”—with examples. Nuance Communications is a software company that provides speech recognition and artificial intelligence solutions. It was acquired by Microsoft in 2022 after merging with ScanSoft, a former competitor in the same field. Learn the meaning of nuance, a word that describes a very slight difference in appearance, meaning, sound, etc. Find synonyms, related words, and examples of nuance in sentences from the Cambridge English Corpus. Although nuance is defined as "a subtle distinction or variation," the adjective subtle is frequently seen modifying the noun: Ms. Fyfield is remarkably thorough in her psychological profiles, giving subtle nuances to characters who are mere passers-by in this psychodrama.