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Learn about hydrocortisone injection , a corticosteroid medication used to treat low corticosteroid levels, allergic reactions, and other conditions. Find out how to use it, what precautions to follow, and what side effects to watch out for. Hydrocortisone is a corticosteroid ( cortisone -like medicine or steroid). It works on the immune system to help relieve swelling, redness, itching, and allergic reactions. This medicine is to be given only by or under the supervision of a doctor. Learn about hydrocortisone injection , a steroid medication that reduces inflammation and treats various conditions. Find out how to use it, what precautions to take, and what side effects to watch out for.