If this happens, abnormal cells may grow into the muscle layer around your uterus (also called an invasive mole). This is rare and happens in less than 15% of people who’ve had a molar pregnancy removed. Hydatidiform mole is an abnormal pregnancy characterized by varying degrees of trophoblastic proliferation (both cytotrophoblast and syncytiotrophoblast) and vesicular swelling of placental villi associated with an absent or abnormal fetus/embryo. Two types of hydatidiform mole, complete and partial, have been described based on both morphologic and cytogenetic criteria (Table 1). 1,2 Epidemiology Epidemiologic studies have reported wide regional variations in the incidence of molar ... A molar pregnancy (hydatidiform mole) is when a mass of tissue grows inside your womb that will not develop into a baby. It is the result of abnormal conception and may cause bleeding or severe vomiting in early pregnancy. Learn about the types, diagnosis, treatment and outlook of molar pregnancy. Gestational Trophoblastic Diseases: Part 1: Complete and Partial Hydatidiform Moles What are gestational trophoblastic diseases? Gestational trophoblastic diseases (GTDs) are a spectrum of tumors and tumor-like conditions characterized by the abnormal proliferation of placental tissue. This proliferation can involve the villous or trophoblastic components of the placenta. GTDs are heterogeneous in presentation, both clinically and histopathologically, and are commonly associated with a ...

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