Ezetimibe Tablets Ezetimibe is a prescription medicine that helps lower the amount of low-density lipoprotein or LDL (“bad” cholesterol) in your blood. It does this by keeping your small intestine from absorbing cholesterol. Healthcare providers may prescribe ezetimibe for people who can’t take statins or can’t lower their cholesterol enough with statins. Generic Name Ezetimibe DrugBank Accession Number DB00973 Background Ezetimibe is a lipid-lowering compound that inhibits intestinal cholesterol and phytosterol absorption. The discovery and research of this drug began in the early 1990s, after the intravenous administration of radiolabelled ezetimibe in rats revealed that it was being localized within enterocytes of the intestinal villi - this prompted studies investigating the effect of ezetimibe on intestinal cholesterol absorption. 3 ... Ezetimibe is a prescription medicine that lowers cholesterol by inhibiting its absorption in the intestines. Learn about its uses, side effects, warnings, interactions, and dosage information from WebMD. Ezetimibe is a medication used in the management and treatment of hypercholesterolemia. It is among a novel class of selective cholesterol-absorption inhibitors. It is indicated to reduce total cholesterol, low-density lipoprotein (LDL), apolipoprotein B (apo B), and non-high-density lipoprotein (HDL) in patients with primary hyperlipidemia, mixed hyperlipidemia, familial hypercholesterolemia (HoFH), and homozygous sitosterolemia (phytosterolemia). This activity describes the indications ...
