The cytoskeleton is a network of filaments and tubules that extends throughout a cell, through the cytoplasm, which is all of the material within a cell except for the nucleus. One moment, please...Please wait while your request is being verified... What is Cytoskeleton? The cytoskeleton is a complex structure that interlinks with the protein of the cell present in the cytoplasm of Prokaryote, Eukaryote, Bacteria, and archaeans. The cytoskeleton is a network of fibers that interlinks all cell organelles and helps the cell to work properly. Cytoskeleton is spread across the cytoplasm and is a complex network of three protein; microtubules, intermediate, and micro filaments.