Cincinnati: At the southwest corner

At the southwest corner of Ohio, sophisticated Cincinnati claims its very own uniquely Buckeye flavor and riverfront appeal. Here are the best things to do there. Cincinnati is Ohio 's third largest city and the largest metro region, and lies on the north bank of the Ohio River in Southwest Ohio in the United States of America. Cincinnati is distinct amongst Midwestern cities. Its culture is a mixture of the Northeast, Old South, Midwest, and Appalachia blended with a strong German-Catholic heritage. It was one of the United States' early boomtowns, and the Over-the-Rhine neighborhood is the largest National Historic District in the country. Today, it ... Breaking Cincinnati news, traffic, weather and local headlines from The Cincinnati Enquirer newspaper. Book these experiences for a close-up look at Cincinnati. These rankings are informed by Tripadvisor data—we consider traveller reviews, ratings, number of page views, and user location. 1. Cincinnati Zoo & Botanical Garden.