Cholesterol is the principal sterol of all animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils. [3][4] Cholesterol is biosynthesized by all animal cells [5] and is an essential structural and signaling component of animal cell membranes. In vertebrates, hepatic cells typically produce the greatest amounts. In the brain, astrocytes produce cholesterol and transport it to neurons. [6] It is absent among prokaryotes (bacteria and archaea ... Cholesterol is a waxy substance throughout the body. It’s not “bad” unless you have too much of it. Your body needs it to build cells and make vitamins and other hormones. But too much cholesterol can pose a problem. Cholesterol comes from two sources. Your liver makes all the cholesterol you need. High levels of “bad” LDL cholesterol may create a buildup of plaque (fatty deposits) in your arteries . This buildup can lead to a heart attack, stroke, or other health problems. High levels of “good” HDL cholesterol may lower your risk for health problems. HDL cholesterol carries cholesterol and plaque to the liver to be flushed out of the body. Cholesterol is a waxy, fat-like substance found in every cell in your body. Learn what a total cholesterol test can reveal.