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Background: Altered sensorium is one of the most common presentations in patients coming to the emergency room. It includes decreased level of consciousness, attention disorder, arousal disorder, and cognitive disorder. The causes of altered sensorium can be varied, some of which are cerebrovascular diseases, alcoholism, cerebral trauma, hypoglycemia, epilepsy, drug intoxication, and neuroinfection. 4–10% of the patients presenting to the emergency department may have altered mental status ... Altered sensorium comprises a group of clinical symptoms rather than a specific diagnosis, and includes cognitive disorders, attention disorders, arousal disorders, and decreased level of consciousness. Altered sensorium is a neurological deficit that changes the brain function varying from consciousness to coma and death. This study assesses the risk factors, causes, and treatment patterns of altered sensorium in a tertiary care hospital in India. METHODS: The study was conducted on 150 patients with altered sensorium of non traumatic origin, over a period of one year at Koppal Institute of Medical Sciences, Koppal after taking consent from patient relatives and ethical committee clearence. All patients of altered sensorium of non-traumatic origin, aged more than 18 years were include in this study. Glasgow coma scale (GCS) is used for primary assessment and also to compare the outcome.