Acute fever is a common complaint in primary care with various infectious and noninfectious causes. This guide provides a stepwise approach for diagnosis and management of acute fever based on literature review and expert consensus. Also, an isolated, acute febrile event in patients with a known inflammatory or neoplastic disorder is still most likely to be infectious. In healthy people, an acute febrile event is unlikely to be the initial manifestation of a chronic illness . Acute febrile illness (AFI) is a fever that subsides within three weeks without a recognized cause. Learn about the common causes, symptoms, and diagnostic methods of AFI, and how to treat it with antimalarial, antibiotic, and antiviral drugs. Get a clear overview of acute febrile illness (AFI), including common causes like infections, symptoms, and diagnostic approaches. Learn about the importance of early diagnosis and treatment for a full recovery.